Antibiotic Use in Infants Ups Risk for Childhood Obesity

Clinical Implications

• Exposure to antibiotic use in children younger than 6 months is associated with elevated body mass scores at ages 10 months, 20 months, and 38 months and overweight at age 38 months. However, such exposure is not linked with overweight or obesity at age 7 years.

http://www.medscape.org/viewarticle/769506?src=cmemp

Does a Healthy Diet Prevent Chronic Disease?

Clinical Implications

• The DASH and Mediterranean diets are examples of healthy eating patterns that have been shown to have beneficial effects on a number of chronic health outcomes.

  Table 1. DASH Diet Food Group Servings for a 2000-Calories-Per-Day Diet

Food Group	Target Serving	Examples of 1 Serving
Low-fat dairy	2-3/day	1 cup milk or yogurt
Grains (mostly whole)	6-8/day	1 slice bread 1 oz dry cereal 1/2 cup cooked rice, pasta, or cereal
Lean meats, poultry, fish	≤6/day	1 oz cooked lean meat, poultry, or fish 1 egg
Nuts/seeds/legumes	4-5/week	1/3 cup or 1 1/2 oz nuts 2 Tbsp peanut butter 2 Tbsp or 1/2 oz seeds 1/2 cup cooked legumes
Fruits	4-5/day	1 medium fruit 1/4 cup dried fruit 1/2 cup fresh, frozen, or canned fruit 1/2 cup fruit juice
Vegetables	4-5/day	1 cup raw leafy vegetables 1/2 cup cut-up raw or cooked vegetables

Adapted from the 2010 Dietary Guidelines for Americans


Table 2. Mediterranean Diet

High in fresh fruits and vegetables, olive oil, legumes, unrefined grains

Moderate in low-fat dairy

Low in meat

Moderate to high in fish

Moderate alcohol intake

http://www.medscape.org/viewarticle/769479?src=cmemp 

Can Long-Acting Beta-Agonists, ICS Cut Asthma Exacerbations?

Clinical Implications

• It did not differ significantly in children receiving Long Acting Beta Agonists (LABAs) plus Inhaled Corticosteroid) ICS vs children receiving higher doses of ICS.
• Compared with children receiving higher ICS doses, those receiving LABAs plus ICS had significantly higher PEF, less use of rescue medication, and greater short-term growth. Adverse events were not significantly different between the groups. 

http://www.medscape.org/viewarticle/770166?src=cmemp

Does Adding Clopidogrel to Aspirin Reduce Stroke Risk?

Clinical Implications

• Among patients with recent lacunar strokes, adding clopidogrel to aspirin did not significantly lower the risk for recurrent stroke.
• Among patients with recent lacunar strokes, adding clopidogrel to aspirin did significantly increase the risk for hemorrhage and death.

http://www.medscape.org/viewarticle/770170?src=cmemp